Which aspect does not fall under the responsibilities of a Principal Investigator?

The role of a Principal Investigator (PI) encompasses a wide range of responsibilities, primarily focused on the oversight and management of the clinical trial at their site. Essential duties include site management, ensuring participant safety, and overseeing data integrity.

Site management involves maintaining the overall operation of the clinical trial, coordinating with staff, and liaising with sponsors and regulatory bodies. Participant safety is paramount, as the PI is responsible for ensuring that the rights, safety, and well-being of trial subjects are protected throughout the study. Similarly, data integrity is crucial and falls under the PI's oversight, as they must ensure that the data collected is accurate, reliable, and ethically obtained.

However, conducting all statistical analyses is typically not a direct responsibility of the Principal Investigator. While the PI may be involved in the planning of statistical methods and might work closely with biostatisticians, the actual execution of statistical analyses is often delegated to specialized personnel, such as biostatisticians or data analysts. Therefore, this aspect does not fall under the direct responsibilities of the Principal Investigator, highlighting the collaborative nature of clinical research where different experts contribute within their domains.